Some genetic diseases cannot be diagnosed by changes in restriction sites. Some of these can be detected by allele-specific oligonucleotide probes. These are

Question:Some genetic diseases cannot be diagnosed by changes in restriction sites. Some of these can be detected by allele-specific oligonucleotide probes. These are

1.copies of the gene with an altered sequence so that a restriction site is inserted

2.mutagenized copies of a gene

3.short sequences that will hybridize only to a specific base sequence

4.PCR-amplified variable numbers of tandem repeats (VNTRs)

Answer:3